Monday, March 8, 2010

NEWER EYE DRUGS FOR GLAUCOMA: RESEARCH AHEAD

A study published in the peer-reviewed medical journal Proceedings of the National Academy of Sciences,and conducted by Dr Alessandro Lambiase and colleagues from the University of Rome, the National Research Council, the Gian Battista Bietti Eye Foundation and the European Brain Research Institute.

Investigations were done on the application of nerve growth factor (NGF) on visual symptoms of glaucoma.NGF are proteins that play a role in the survival of nerve cells. Use of this appears to prevent, and even reverse, glaucoma’s characteristic pressure damage to the eyeballs of both rats and humans. This small study has encouraging findings, with humans experiencing improvements in visual clarity and contrast. Two of the patients showed an improvement in their visual field too. However, with only three subjects the study is too small to draw concrete conclusions.Research like this is usually followed by more investigations on potential new treatments, and only the results of long-term, randomised controlled trials will provide definitive answers about the potential benefits of using NGF eye drops.

More details: www.nhs.uk/news/2009/08August/Pages/GlaucomaEyeDropCure.aspx

Sunday, March 7, 2010

NEWER EYE MEDICATIONS: DIABETIC RETINOPATHY,EYE ALLERGY....

In DIABETES, a journal by the American Diabetes Association the role of Topical Administration of Nepafenac showed Inhibition of Diabetes-Induced Retinal Microvascular Disease and Underlying Abnormalities of Retinal Metabolism and Physiology.Professor Timothy S. Kern noted pharmacologic treatment of diabetic retinopathy via topical Nepafenac, an anti-inflammatory drug known to reach the retina when administered via eyedrops, on the development of early stages of diabetic retinopathy and on metabolic and physiologic abnormalities that contribute to the retinal disease.

Topical antihistamines & decongestants
Eye allergy drugs or Antihistamine eyedrops work by blocking histamine receptors in the conjunctiva. The histamine, therefore, is unable to attach to the conjunctiva and exert its effects. They are effective in relieving itching but have little impact on swelling or redness. They have advantages over antihistamine tablets; there is a faster onset of action and less drying of the eye. The new generation of topical antihistamines includes emedastine difumarate (Emadine) and levocabastine (Livostin). Patanol, a topical mast-cell stabilizer, is a safe, highly effective, long-acting treatment.). Side effects of few combination antihistamine-decongestant preparations are minimal, but the drops may become less effective if used for prolonged periods. They do have a potential for abuse and should not be used by people with narrow-angle glaucoma.